All the Publications

November 17, 2014

Iron- and Cobalt-Catalyzed Arylation of Azetidines, Pyrrolidines, and Piperidines with Grignard Reagents.

Barré B1, Gonnard L, Campagne R, Reymond S, Marin J, Ciapetti P, Brellier M, Guérinot A, Cossy J. 

Org Lett. 2014 Nov 17. [Epub ahead of print]
July 15, 2013

Small molecules inhibit the interaction of Nrf2 and the Keap1 Kelch domain through a non-covalent mechanism.

Marcotte D, Zeng W, Hus JC, McKenzie A, Hession C, Jin P, Bergeron C, Lugovskoy A, Enyedy I, Cuervo H, Wang D, Atmanene C, Roecklin D, Vecchi M, Vivat V, Kraemer J, Winkler D, Hong V, Chao J, Lukashev M, Silvian L.

Bioorg Med Chem. 2013 Jul 15;21(14):4011-9. doi: 10.1016/j.bmc.2013.04.019. Epub 2013 Apr 19.
April 22, 2013

In silico fragment-based drug discovery: setup and validation of a fragment-to-lead computational protocol using S4MPLE.

Hoffer L, Renaud JP, Horvath D.

J Chem Inf Model. 2013 Apr 22;53(4):836-51. doi: 10.1021/ci4000163. Epub 2013 Apr 11.
June 5, 2012

Exploring key parameters to detect subtle ligand-induced protein conformational changes using traveling wave ion mobility mass spectrometry.

Atmanene C, Petiot-Bécard S, Zeyer D, Van Dorsselaer A, Vivat Hannah V, Sanglier-Cianférani S.

Anal Chem. 2012 Jun 5;84(11):4703-10. doi: 10.1021/ac203223h. Epub 2012 May 21.
April 20, 2012

Discovery of specific inhibitors of human USP7/HAUSP deubiquitinating enzyme.

Reverdy C, Conrath S, Lopez R, Planquette C, Atmanene C, Collura V, Harpon J, Battaglia V, Vivat V, Sippl W, Colland F.

Chem Biol. 2012 Apr 20;19(4):467-77. doi: 10.1016/j.chembiol.2012.02.007.
January 11, 2012

Mild chemo-selective hydration of terminal alkynes catalysed by AgSbF6.

Thuong MB, Mann A, Wagner A.

Chem Commun (Camb). 2012 Jan 11;48(3):434-6. doi: 10.1039/c1cc12928g. Epub 2011 Nov 15.
August 15, 2011

Characterization of novel checkpoint kinase 1 inhibitors by in vitro assays and in human cancer cells treated with topoisomerase inhibitors.

Ferry G, Studeny A, Bossard C, Kubara PM, Zeyer D, Renaud JP, Casara P, de Nanteuil G, Wierzbicki M, Pfeiffer B, Prudhomme M, Leonce S, Pierré A, Boutin JA, Golsteyn RM.

Life Sci. 2011 Aug 15;89(7-8):259-68. doi: 10.1016/j.lfs.2011.06.010. Epub 2011 Jun 29.
July 22, 2011

Antibody purification by affinity chromatography based on small molecule affinity ligands identified by SPR-based screening of chemical microarrays.

Arnold M, Bittermann H, Kalbfuss-Zimmermann B, Neumann T, Schmidt K, Sekul R, Hilbrig F, Ludolph H, Freitag R.

J Chromatogr A. 2011 Jul 22;1218(29):4649-59. doi: 10.1016/j.chroma.2011.05.040. Epub 2011 May 18.
July 1, 2011

Fragment-based drug design: computational & experimental state of the art.

Hoffer L, Renaud JP, Horvath D.

Comb Chem High Throughput Screen. 2011 Jul;14(6):500-20. Review.
January 1, 2010

Native MS: an 'ESI' way to support structure- and fragment-based drug discovery.

Vivat Hannah V, Atmanene C, Zeyer D, Van Dorsselaer A, Sanglier-Cianférani S.

Future Med Chem. 2010 Jan;2(1):35-50. doi: 10.4155/fmc.09.141.