Cryo-electron microscopy has been distinguished by the 2017 Nobel Prize in chemistry for the “high-resolution structure determination of biomolecules in solution”. The pioneering NovAliX- Thermo Fisher Scientific (formerly FEI)- joint cryo-EM laboratory – provides access to an industrial quality research service complementing our X-ray crystallography capabilities.
NovAliX’s cryo-EM workflow is optimized to meet the expectations of the pharmaceutical industry; addressing critical issues in the discovery of drugs, biologics and in the characterization of viral vectors and biosimilars by direct visualization: from low resolution negative stain 2D images, to high resolution 3D structures.
Today we are proud to highlight to the community a recent article in Nature Reviews Drug Discovery “Cryo-EM in drug discovery: achievements, limitations and prospects” co-authored by leading scientists including NovAliX experts.